Study Name: Measurement of Serum Des-γ-Carboxy Prothrombin (DCP) for Early Detection of Hepatocellular Carcinoma (HCC) in Patients with Chronic Hepatitis C Virus (HCV ) Infection Separate Consent Form: No Withdrawal Form: No Eligible Patients: Randomized patients (Lead-in, Express, and Breakthrough/Relapser)

K.10: DCP Ancillary Study Updated: 12/01/2004 Snap Shot Page 1 of 1 DCP Snap Shot Sites Participating: All sites and all patients in the HALT-C Trial Principal Investigator: Anna S.F. Lok, MD (University of Michigan) Co-Investigator: Leonard Seeff, MD Study Name: Measurement of Serum Des-γ-Carboxy Prothrombin (DCP) for Early Detection of Hepatocellular Carcinoma (HCC) in Patients with Chronic Hepatitis C Virus (HCV ) Infection Separate Consent Form: No Withdrawal Form: No Eligible Patients: Randomized patients (Lead-in, Express, and Breakthrough/Relapser) Visit Schedule (additional data/specimen and forms for AS) Note: “X” means all participating sites take part. No additional specimens are collected for this study. Tests are performed on specimens collected for the Steatosis Ancillary Study (seq.#121) or on the specimens stored for the main trial (seq.#110, seq.#111 or seq.#123). DCP results are maintained in a separate data file and are not included in the main HALT-C database.